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Concurrent administration with cysteine or N-acetylcysteine enhances hepatic sulfate production, which could alter acetaminophen metabolism and should be considered when treating patients with chronic pain requiring frequent analgesia

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May 2023

Because of this and the fact that the body only needs a small amount of vitamin B12 each day, it can take up to a year or even longer for an inadequate vitamin B12 to manifest as an apparent deficiency